Factors impacting on progress towards elimination of transmission of schistosomiasis japonica in China
Open Access
- 3 December 2012
- journal article
- review article
- Published by Springer Science and Business Media LLC in Parasites & Vectors
- Vol. 5 (1), 275-7
- https://doi.org/10.1186/1756-3305-5-275
Abstract
Over the past decades China has made a great stride in controlling schistosomiasis, eliminating transmission of Schistosoma japonicum in 5 provinces and remarkably reducing transmission intensities in the rest of the seven endemic provinces. Recently, an integrated control strategy, which focuses on interventions on humans and bovines, has been implemented throughout endemic areas in China. This strategy assumes that a reduction in transmission of S. japonicum from humans and bovines to the intermediate Oncomelania snail host would eventually block the transmission of this parasite, and has yielded effective results in some endemic areas. Yet the transmission of S. japonicum is relatively complicated – in addition to humans and bovines, more than 40 species of mammalians can serve as potential zoonotic reservoirs. Here, we caution that some factors – potential roles of other mammalian reservoirs and human movement in sustaining the transmission, low sensitivity/specificity of current diagnostic tools for infections, praziquantel treatment failures, changes in environmental and socio-economic factors such as flooding in key endemic areas - may pose great obstacles towards transmission interruption of the parasite. Assessing potential roles of these factors in the transmission and implications for current control strategies aiming at transmission interruption is needed.Keywords
This publication has 41 references indexed in Scilit:
- The South-to-North Water Diversion Project: effect of the water diversion pattern on transmission of Oncomelania hupensis, the intermediate host of Schistosoma japonicum in ChinaParasites & Vectors, 2012
- Toward Sustainable and Comprehensive Control of Schistosomiasis in China: Lessons from SichuanPLoS Neglected Tropical Diseases, 2011
- A diagnostic challenge for schistosomiasis japonica in China: consequences on praziquantel-based morbidity controlParasites & Vectors, 2011
- An Integrated Strategy for Transmission Control of Schistosoma japonicum in a Marshland Area of China: Findings from a Five-Year Longitudinal Survey and Mathematical ModelingThe American Journal of Tropical Medicine and Hygiene, 2011
- Diagnosis of Schistosoma haematobium by Detection of Specific DNA Fragments from Filtered Urine SamplesThe American Journal of Tropical Medicine and Hygiene, 2011
- Development and Evaluation of a Sensitive PCR-ELISA System for Detection of Schistosoma Infection in FecesPLoS Neglected Tropical Diseases, 2010
- Diagnosing Schistosomiasis by Detection of Cell-Free Parasite DNA in Human PlasmaPLoS Neglected Tropical Diseases, 2009
- Transmission Dynamics of Schistosoma japonicum in the Lakes and Marshlands of ChinaPLOS ONE, 2008
- Population Genetics of Schistosoma japonicum within the Philippines Suggest High Levels of Transmission between Humans and DogsPLoS Neglected Tropical Diseases, 2008
- Multi-Host Transmission Dynamics of Schistosoma japonicum in Samar Province, the PhilippinesPLoS Medicine, 2008