Biomonitoring of organophosphate exposure of pesticide sprayers and comparison of exposure levels with other population groups in Thessaly (Greece)
- 1 November 2013
- journal article
- exposure assessment
- Published by BMJ in Occupational and Environmental Medicine
- Vol. 71 (2), 126-133
- https://doi.org/10.1136/oemed-2013-101490
Abstract
Objectives To evaluate the exposure of different population groups in Thessaly (Greece) to organophosphate pesticides (OPs) and investigate the dependence of exposure levels on pesticide application practices, personal protective and hygienic measures taken. Methods For the exposure assessment, four dialkyl phosphate (DAP) metabolites of organophosphate pesticides were quantified in spot urine samples of 77 pesticide sprayers, 75 residents of the studied agricultural area non-involved in agricultural activities and 112 urban residents who served as a control group. Structured questionnaires were used to record demographic characteristics, pesticide application parameters and protective measures taken. Univariate and multivariate analysis of the obtained cross-sectional data was performed to identify potential risk factors associated with biomarker levels. Results It was found that total DAP median level in the sprayers’ group was 24.9 μg/g creatinine (IQR: 13.0–42.1), while the rural and urban residents had significantly lower (pConclusions Our study findings confirm the increased exposure to OPs in pesticide sprayers and underline the importance of protective measures especially those that focus on dermal exposure mitigation.Keywords
This publication has 32 references indexed in Scilit:
- Associations of Prenatal Exposure to Organophosphate Pesticide Metabolites with Gestational Age and Birth WeightEnvironmental Health Perspectives, 2012
- The atlas of dialkylphosphates; assessment of cumulative human organophosphorus pesticides’ exposureForensic Science International, 2012
- Occupational Pesticide Exposures and Cancer Risk: A ReviewJournal of Toxicology and Environmental Health, Part B, 2012
- Organophosphorous pesticides research in Mexico: epidemiological and experimental approachesToxicology Mechanisms and Methods, 2011
- Urinary Concentrations of Dialkylphosphate Metabolites of Organophosphorus Pesticides: National Health and Nutrition Examination Survey 1999–2004International Journal of Environmental Research and Public Health, 2011
- Male reproductive toxicity of organophosphorous compounds: a reviewToxicological & Environmental Chemistry, 2011
- Endocrine disrupting pesticides: Implications for risk assessmentEnvironment International, 2008
- Organophosphate Pesticide Exposure and Neurobehavioral Performance in Agricultural and Nonagricultural Hispanic WorkersEnvironmental Health Perspectives, 2006
- Twenty-four-hour urinary excretion of ten pesticide metabolites in healthy adults in two different areas of Italy (Florence and Ragusa)Science of The Total Environment, 2004
- Metabolites of Organophosphorous Insecticides in Urine Specimens from Inhabitants of a Residential AreaEnvironmental Research, 2001