Male reproductive toxicity of organophosphorous compounds: a review
- 6 June 2011
- journal article
- review article
- Published by Informa UK Limited in Toxicological & Environmental Chemistry
- Vol. 93 (7), 1486-1507
- https://doi.org/10.1080/02772248.2011.581874
Abstract
Fertility is declining in many countries and there has been substantial interest in the potential adverse effects of exposure to environmental hazardous chemicals, including pesticides on male reproduction. Organophosphorous compounds (organophosphates, OP) constitute a heterogeneous category of chemicals specifically designed for the control of pests or plant diseases. OP are known to produce reproductive toxicity, resulting in a decrease in the fertility levels of humans and animals. This review article mainly focused on toxicity of some OP such as acephate, chlorpyrifos, diazinon, dimethoate, fenitrothion, malathion, and monocrotophos especially dealing with reproductive toxicity in males. Furthermore, this review deals with mode of action and clinical syndromes of OP. Considerable lab studies on animals concluded that OP produce adverse effects on male reproductive system.Keywords
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