The Thrombospondin Motif of Aggrecanase-1 (ADAMTS-4) Is Critical for Aggrecan Substrate Recognition and Cleavage
Open Access
- 1 August 2000
- journal article
- Published by Elsevier BV
- Vol. 275 (33), 25791-25797
- https://doi.org/10.1074/jbc.m001065200
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Sites of Aggrecan Cleavage by Recombinant Human Aggrecanase-1 (ADAMTS-4)Journal of Biological Chemistry, 2000
- Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS FamilyPublished by Elsevier BV ,1999
- Purification and Cloning of Aggrecanase-1: A Member of the ADAMTS Family of ProteinsScience, 1999
- The Exon/Intron Organization and Chromosomal Mapping of the Mouse ADAMTS-1 Gene Encoding an ADAM Family Protein with TSP MotifsGenomics, 1997
- Interactions of pentosan polysulfate with cartilage matrix proteins and synovial fibroblasts derived from patients with osteoarthritisOsteoarthritis and Cartilage, 1996
- Degradation of cartilage aggrecan by collagenase‐3 (MMP‐13)FEBS Letters, 1996
- Cell-mediated Catabolism of AggrecanPublished by Elsevier BV ,1995
- Cartilage oligomeric matrix protein and thrombospondin 1European Journal of Biochemistry, 1994
- The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain.JCI Insight, 1992
- Methotrexate, a high-affinity pseudosubstrate of dihydrofolate reductaseBiochemistry, 1979