Mitochondrial DNA sequence divergence among some west European brown bear (Ursus arctos L.) populations. Lessons for conservation
- 1 November 1994
- journal article
- Published by Springer Science and Business Media LLC in Heredity
- Vol. 73 (5), 480-489
- https://doi.org/10.1038/hdy.1994.146
Abstract
We used the polymerase chain reaction and nucleotide sequencing to study mitochondrial DNA (mtDNA) genetic variability of brown bears (Ursus arctos) belonging to some western European populations. Demographic decline and isolation have apparently shaped genetic variability within and between populations. Small relict bear populations were apparently monomorphic and fixed for different mtDNA haplotypes. Genetic relationships among mtDNA haplotypes suggested the existence of a phylogeographic structure. We discuss the possible roles of historical and demographic factors in determining the observed genetic patterns. The low genetically effective size of the studied brown bear populations points to risks of continuing future loss of gene diversity and increase in inbreeding. Artificial gene flow through restocking could alleviate inbreeding depression in small isolated brown bear populations, and mtDNA phylogeographic relationships may provide a framework for their genetic management.Keywords
This publication has 17 references indexed in Scilit:
- Excrement analysis by PCRNature, 1992
- Interspecific and intraspecific mitochondrial DNA variation in North American bears (Ursus)Canadian Journal of Zoology, 1991
- A role for molecular genetics in the recognition and conservation of endangered speciesTrends in Ecology & Evolution, 1989
- Genetically Effective Population Size of Large Mammals: An Assessment of EstimatorsConservation Biology, 1989
- Genetics and Demography in Biological ConservationScience, 1988
- INTRASPECIFIC PHYLOGEOGRAPHY: The Mitochondrial DNA Bridge Between Population Genetics and SystematicsAnnual Review of Ecology and Systematics, 1987
- Genetics and the conservation of grizzly bearsTrends in Ecology & Evolution, 1986
- MITOCHONDRIAL-DNA AND 2 PERSPECTIVES ON EVOLUTIONARY GENETICSBiological Journal of the Linnean Society, 1985
- Sequence and organization of the human mitochondrial genomeNature, 1981
- A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequencesJournal of Molecular Evolution, 1980