Social regulation of gene expression in human leukocytes
Open Access
- 13 September 2007
- journal article
- Published by Springer Science and Business Media LLC in Genome Biology
- Vol. 8 (9), R189
- https://doi.org/10.1186/gb-2007-8-9-r189
Abstract
Social environmental influences on human health are well established in the epidemiology literature, but their functional genomic mechanisms are unclear. The present study analyzed genome-wide transcriptional activity in people who chronically experienced high versus low levels of subjective social isolation (loneliness) to assess alterations in the activity of transcription control pathways that might contribute to increased adverse health outcomes in social isolates.This publication has 65 references indexed in Scilit:
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