One pot synthesis of selenocysteine containing peptoid libraries by Ugi multicomponent reactions in water
- 15 December 2005
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 5,p. 541-543
- https://doi.org/10.1039/b514597j
Abstract
Selenocysteine containing peptoids and peptide–peptoid conjugates were synthesized by combinatorial Ugi-MCRs (multicomponent reactions) in water: for the first time, an acetal (selenoacetal 2a) was used in Ugi-MCR to furnish selenocysteine peptoids in one step as model compounds for selenocysteine peptides and proteins.Keywords
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