Environmental Macrolide–Lincosamide–Streptogramin and Tetracycline Resistant Bacteria
Open Access
- 1 January 2011
- journal article
- Published by Frontiers Media SA in Frontiers in Microbiology
- Vol. 2, 40
- https://doi.org/10.3389/fmicb.2011.00040
Abstract
Bacteria can become resistant to antibiotics by mutation, transformation and/or acquisition of new genes which are normally associated with mobile elements (plasmids, transposons, and integrons). Mobile elements are the main driving force in horizontal gene transfer between strains, species and genera and are responsible for the rapid spread of particular elements throughout a bacterial community and between ecosystems. Today, antibiotic resistant bacteria are widely distributed throughout the world and have even been isolated from environments that are relatively untouched by human civilization. In this review macrolides, lincosamides, streptogramins, and tetracycline resistance genes and bacteria will be discussed with an emphasis on the resistance genes which are unique to environmental bacteria which are defined for this review as species and genera that are primarily found outside of humans and animals.This publication has 61 references indexed in Scilit:
- Revisiting the structures of several antibiotics bound to the bacterial ribosomeProceedings of the National Academy of Sciences of the United States of America, 2010
- Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug actionProceedings of the National Academy of Sciences of the United States of America, 2010
- Genomewide Analysis of Divergence of Antibiotic Resistance Determinants in Closely Related Isolates of Acinetobacter baumanniiAntimicrobial Agents and Chemotherapy, 2010
- The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibioticsProceedings of the National Academy of Sciences of the United States of America, 2010
- Horizontal Transfer of Tetracycline Resistance among Chlamydia spp. In VitroAntimicrobial Agents and Chemotherapy, 2009
- Novel ABC Transporter Gene, vga (C), Located on a Multiresistance Plasmid from a Porcine Methicillin-Resistant Staphylococcus aureus ST398 StrainAntimicrobial Agents and Chemotherapy, 2009
- A novel transposon, Tn6009, composed of a Tn916 element linked with a Staphylococcus aureus mer operonJournal of Antimicrobial Chemotherapy, 2008
- A New Evolutionary Variant of the Streptogramin A Resistance Protein, Vga(A) LC , from Staphylococcus haemolyticus with Shifted Substrate Specificity towards LincosamidesAntimicrobial Agents and Chemotherapy, 2006
- Intrinsic Macrolide Resistance in Rapidly Growing MycobacteriaAntimicrobial Agents and Chemotherapy, 2006
- Sampling the Antibiotic ResistomeScience, 2006