Axonal regeneration through acellular muscle grafts
Open Access
- 1 January 1997
- journal article
- review article
- Published by Wiley in Journal of Anatomy
- Vol. 190 (1), 57-71
- https://doi.org/10.1046/j.1469-7580.1997.19010057.x
Abstract
The management of peripheral nerve injury remains a major clinical problem. Progress in this field will almost certainly depend upon manipulating the pathophysiological processes which are triggered by traumatic injuries. One of the most important determinants of functional outcome after the reconstruction of a transected peripheral nerve is the length of the gap between proximal and distal nerve stumps. Long defects (> 2 cm) must be bridged by a suitable conduit in order to support axonal regrowth. This review examines the cellular and acellular elements which facilitate axonal regrowth and the use of acellular muscle grafts in the repair of injuries in the peripheral nervous system.This publication has 99 references indexed in Scilit:
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