Intercontinental Spread of Pyrimethamine-Resistant Malaria
Top Cited Papers
- 20 August 2004
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 305 (5687), 1124
- https://doi.org/10.1126/science.1098876
Abstract
Here we present molecular evidence demonstrating that malaria parasites bearing high-level pyrimethamine resistance originally arrived in Africa from southeast Asia. The resistance alleles carried by these migrants are now spreading across Africa at an alarming rate, signaling the end of affordable malaria treatment and presenting sub-Saharan Africa with a public health crisis.This publication has 9 references indexed in Scilit:
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