Mutations inPlasmodium falciparumDihydrofolate Reductase and Dihydropteroate Synthase and Epidemiologic Patterns of Pyrimethamine‐Sulfadoxine Use and Resistance

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Abstract
To assess the relationship between mutations in Plasmodium falciparum dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) and clinical