Health Psychology: Developing Biologically Plausible Models Linking the Social World and Physical Health
- 1 January 2009
- journal article
- review article
- Published by Annual Reviews in Annual Review of Psychology
- Vol. 60 (1), 501-524
- https://doi.org/10.1146/annurev.psych.60.110707.163551
Abstract
Research over the past several decades has documented psychosocial influences on the development and progression of several major medical illnesses. The field is now increasingly focused on identifying the biological and behavioral mechanisms underlying these effects. This review takes stock of the knowledge accumulated in the biological arena to date and highlights conceptual and methodological approaches that have proven especially productive. It emphasizes the value of a disease-centered approach that “reverse engineers” adverse health outcomes into their specific biological determinants and then identifies psychologically modulated neuroendocrine and immunologic dynamics that modulate those pathological processes at the cellular and molecular levels.Keywords
This publication has 139 references indexed in Scilit:
- Social regulation of leukocyte homeostasis: The role of glucocorticoid sensitivityBrain, Behavior, and Immunity, 2008
- A Functional Genomic Fingerprint of Chronic Stress in Humans: Blunted Glucocorticoid and Increased NF-κB SignalingBiological Psychiatry, 2008
- Stress-induced remodeling of lymphoid innervationBrain, Behavior, and Immunity, 2008
- Stress and inflammation in exacerbations of asthmaBrain, Behavior, and Immunity, 2007
- Psychological Stress and DiseaseJama-Journal Of The American Medical Association, 2007
- Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depressionBrain, Behavior, and Immunity, 2007
- Association of Childhood Socioeconomic Status With Subsequent Coronary Heart Disease in PhysiciansArchives of Internal Medicine, 2006
- Inherited epigenetic variation — revisiting soft inheritanceNature Reviews Genetics, 2006
- Epigenetic programming by maternal behaviorNature Neuroscience, 2004
- Inflammation and cancerNature, 2002