The changing face of Parkinson's disease‐associated psychosis: A cross‐sectional study based on the new NINDS‐NIMH criteria
- 26 April 2010
- journal article
- research article
- Published by Wiley in Movement Disorders
- Vol. 25 (6), 763-766
- https://doi.org/10.1002/mds.22839
Abstract
New criteria for Parkinson's disease‐associated psychosis (PDAP) were recently proposed by a NINDS‐NIMH working group. We assessed 116 consecutive unselected outpatients with PD for the existence of psychotic symptoms during the previous month, using a structured questionnaire covering the whole spectrum of PDAP symptoms. Hallucinations occurred in 42% of the patients (visual: 16%; nonvisual: 35%), delusions in 4%, and minor symptoms in 45% (sense of presence, visual illusions, or passage hallucinations). The prevalence of PDAP was 43% when the usual definition was used (hallucinations and/or delusions) and 60% when the NINDS‐NIHM criteria were used. Correlations between PDAP and patient characteristics varied with the definition of PDAP. These findings suggest that the epidemiology of PDAP should be re‐evaluated with the new criteria. Minor symptoms and nonvisual hallucinations are an important part of the PDAP spectrum, which has commonly been restricted to visual hallucinations and delusions. © 2010 Movement Disorder SocietyThis publication has 15 references indexed in Scilit:
- When a Parkinson's disease patient starts to hallucinatePractical Neurology, 2008
- A questionnaire-based (UM-PDHQ) study of hallucinations in Parkinson's diseaseBMC Neurology, 2008
- Scales to assess psychosis in Parkinson's disease: Critique and recommendationsMovement Disorders, 2008
- Using the presence of visual hallucinations to differentiate Parkinson's disease from atypical parkinsonismJournal of Neurology, Neurosurgery & Psychiatry, 2007
- Age‐related influences on the clinical characteristics of new‐onset hallucinations in Parkinson's disease patientsMovement Disorders, 2006
- Proposed dose equivalence for rapid switch between dopamine receptor agonists in Parkinson's disease: A review of the literatureClinical Therapeutics, 2006
- Drug-Induced Psychosis in Parkinson DiseaseClinical Neuropharmacology, 2005
- Relationship between hallucinations, delusions, and rapid eye movement sleep behavior disorder in Parkinson's diseaseMovement Disorders, 2005
- Repeated visual hallucinations in Parkinson's disease as disturbed external/internal perceptions: Focused review and a new integrative modelMovement Disorders, 2004
- The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease.Journal of Neurology, Neurosurgery & Psychiatry, 1988