A new permanent cell line derived from the bank vole (Myodes glareolus) as cell culture model for zoonotic viruses
Open Access
- 5 July 2011
- journal article
- Published by Springer Science and Business Media LLC in Virology Journal
- Vol. 8 (1), 339
- https://doi.org/10.1186/1743-422x-8-339
Abstract
Approximately 60% of emerging viruses are of zoonotic origin, with three-fourths derived from wild animals. Many of these zoonotic diseases are transmitted by rodents with important information about their reservoir dynamics and pathogenesis missing. One main reason for the gap in our knowledge is the lack of adequate cell culture systems as models for the investigation of rodent-borne (robo) viruses in vitro. Therefore we established and characterized a new cell line, BVK168, using the kidney of a bank vole, Myodes glareolus, the most abundant member of the Arvicolinae trapped in Germany.Keywords
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