GLIOMA EXTENT OF RESECTION AND ITS IMPACT ON PATIENT OUTCOME
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- 1 April 2008
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurosurgery
- Vol. 62 (4), 753-766
- https://doi.org/10.1227/01.neu.0000318159.21731.cf
Abstract
There is still no general consensus in the literature regarding the role of extent of glioma resection in improving patient outcome. Although the importance of resection in obtaining tissue diagnosis and alleviating symptoms is clear, a lack of Class I evidence prevents similar certainty in assessing the influence of extent of resection. We reviewed every major clinical publication since 1990 on the role of extent of resection in glioma outcome. Twenty-eight high-grade glioma articles and 10 low-grade glioma articles were examined in terms of quality of evidence, expected extent of resection, and survival benefit. Despite persistent limitations in the quality of data, mounting evidence suggests that more extensive surgical resection is associated with longer life expectancy for both low- and high-grade gliomas.Keywords
This publication has 57 references indexed in Scilit:
- Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trialThe Lancet Oncology, 2006
- Glioblastoma multiforme—report of 267 cases treated at a single institutionSurgical Neurology, 2005
- Debulking or biopsy of malignant glioma in elderly people – a randomised studyActa Neurochirurgica, 2003
- A phase III study of radiation therapy plus carmustine with or without recombinant interferon-? in the treatment of patients with newly diagnosed high-grade gliomaCancer, 2001
- Prognostic implications of the extent of surgical resection in patients with intracranial malignant gliomasCancer, 1995
- Influence of extent of surgery and tumor location on treatment outcome of patients with glioblastoma multiforme treated with combined modality approachJournal of Neuro-Oncology, 1994
- Supratentorial low-grade astrocytoma. Correlation of computed tomography findings with effect of radiation therapy and prognostic variablesCancer, 1993
- A randomized study of chemotherapy with procarbazine, vincristine, and lomustine with and without radiation therapy for astrocytoma grades 3 and/or 4Cancer, 1991
- The influence of the extent of surgery on the neurological function and survival in malignant glioma. A retrospective analysis in 243 patients.Journal of Neurology, Neurosurgery & Psychiatry, 1990
- Neurosurgical management of low-grade astrocytoma of the cerebral hemispheresJournal of Neurosurgery, 1984