Recent developments in microfluidics-based chemotaxis studies
- 28 May 2013
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Lab on a Chip
- Vol. 13 (13), 2484-2499
- https://doi.org/10.1039/c3lc50415h
Abstract
Microfluidic devices can better control cellular microenvironments compared to conventional cell migration assays. Over the past few years, microfluidics-based chemotaxis studies showed a rapid growth. New strategies were developed to explore cell migration in manipulated chemical gradients. In addition to expanding the use of microfluidic devices for a broader range of cell types, microfluidic devices were used to study cell migration and chemotaxis in complex environments. Furthermore, high-throughput microfluidic chemotaxis devices and integrated microfluidic chemotaxis systems were developed for medical and commercial applications. In this article, we review recent developments in microfluidics-based chemotaxis studies and discuss the new trends in this field observed over the past few years.Keywords
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