Newly diagnosed diabetes mellitus, DKA, and COVID-19: Causality or coincidence? A report of three cases
- 1 February 2021
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 93 (2), 1150-1153
- https://doi.org/10.1002/jmv.26339
Abstract
Novel coronavirus disease 2019 (COVID-19), a 2020 pandemic, has resulted in an unexpected loss in lives, quality of life, and the economy. The COVID-19 clinical spectrum varies from asymptomatic to death, and its complications may involve various organs. Notwithstanding, the impact of COVID-19 on endocrine systems is understudied. Previous coronavirus outbreaks such as severe acute respiratory syndrome coronavirus can cause new-onset diabetes mellitus (DM). However, there were only two previous case reports on newly diagnosed DM in COVID-19 patients. Here, we described three patients who had newly diagnosed DM associated with COVID-19. COVID-19 likely unmasked existing DM by aggravating its metabolic complications rather than causing the new-onset DM in these patients. However, more research is needed to evaluate if there is a casual relationship between the development of DM, DKA, and COVID-19.This publication has 8 references indexed in Scilit:
- Impaired glucose metabolism in patients with diabetes, prediabetes, and obesity is associated with severe COVID-19Journal of Medical Virology, 2021
- Why obesity, hypertension, diabetes, and ethnicities are common risk factors for COVID-19 and H1N1 influenza infectionsJournal of Medical Virology, 2021
- Newly diagnosed diabetes and diabetic ketoacidosis precipitated by COVID-19 infectionThe American Journal of Emergency Medicine, 2020
- New-Onset Diabetes in Covid-19The New England Journal of Medicine, 2020
- Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitusDiabetes Research and Clinical Practice, 2020
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort studyThe Lancet, 2020
- A new coronavirus associated with human respiratory disease in ChinaNature, 2020
- Binding of SARS coronavirus to its receptor damages islets and causes acute diabetesActa Diabetologica, 2009