STRATIFICATION OF PENILE VASCULAR PATHOLOGIES IN PATIENTS WITH PEYRONIE’S DISEASE AND IN MEN WITH ERECTILE DYSFUNCTION ACCORDING TO AGE: A COMPARATIVE STUDY
- 1 July 2004
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Urology
- Vol. 172 (1), 259-262
- https://doi.org/10.1097/01.ju.0000132154.38285.c7
Abstract
Erectile dysfunction (ED) occurs in 20% to 54% of men with Peyronie’s disease (PD). We investigated the role of vascular status in the pathophysiology of ED in patients with PD. A total of 509 consecutive men with PD (group 1—impotent 259, 1a, and potent 250, 1b, mean age ± SD 54.6 ± 4.4 years) and 507 consecutive men with ED only (group 2—mean age 49.4 ± 12.4 years) underwent penile duplex ultrasonography (PDU). Detailed sexual and medical history, and focused physical examination were performed in all patients. Patients in the 2, groups were stratified according to age (18 to 80 years) and classified according to PDU results (normal vascular status, arterial insufficiency, veno-occlusive dysfunction [VOD] and mixed vascular pathology). VOD was observed in 23.1% and 42.8% of patients in groups 1 and 2, respectively (p 0.05). Of note, mixed vascular pathologies were significantly higher in group 1a than in group 2 in the third through fifth decades (p <0.05), while arterial insufficiency was more common in the seventh decade (p <0.05). While many groups have investigated the vascular causes of ED, the exact etiology of ED in men with PD remains controversial. A possible relationship between ED and VOD in patients with PD has been previously reported. The current PDU study demonstrates that for all ages except 30 to 39 years the prevalence of VOD in patients with PD plus ED is similar to that of patients with ED alone.Keywords
This publication has 20 references indexed in Scilit:
- Relationship Between the Severity of Penile Curvature and the Presence of Comorbidities in Men With Peyronie's DiseaseJournal of Urology, 2004
- Peyronie’s Disease: A ReviewJournal of Urology, 2003
- A Retrospective Review of 307 Men With Peyronie’s DiseaseJournal of Urology, 2002
- PEYRONIE'S DISEASEUrologic Clinics of North America, 2001
- Color Doppler ultrasound assessment of penile vascular system in men with Peyronie's diseaseInternational Journal Of Impotence Research, 2000
- Sexual Dysfunction in Peyronie's Disease: An Analysis of 222 Patients Without Previous Local Plaque TherapyJournal of Urology, 1997
- Penile Vascular Assessment Using Color Duplex Sonography in Men with Peyronie's DiseaseJournal of Urology, 1996
- Pre‐operative Assessment of Peyronie's Disease Using Colour Doppler SonographyBritish Journal of Urology, 1992
- Classification of Congenital and Acquired Penile DeviationUrologia Internationalis, 1983
- PEYRONIE'S DISEASE ASSOCIATED WITH CHRONIC DEGENERATIVE ARTERIAL DISEASE AND NOT WITH BETA-ADRENOCEPTOR BLOCKING AGENTSThe Lancet, 1982