Modelling selective activation of small myelinated nerve fibres using a monopolar point electrode
- 1 November 1995
- journal article
- modelling
- Published by Springer Science and Business Media LLC in Medical & Biological Engineering & Computing
- Vol. 33 (6), 762-768
- https://doi.org/10.1007/bf02523007
Abstract
The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the sensitivity of excitation and blocking threshold currents of nerve fibres to fibre diameter, electrode-fibre distance and pulse duration has been simulated by a computer model. A simple infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical properties of a myelinated nerve fibre. The results show that selective activation of small myelinated fibres may be possible in a region at some distance from the electrode.Keywords
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