Performance of the Molecular Alere i Influenza A&B Test Compared to That of the Xpert Flu A/B Assay
Open Access
- 1 February 2015
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 53 (2), 706-709
- https://doi.org/10.1128/jcm.02783-14
Abstract
Data on the performance of rapid molecular point-of-care use platforms for diagnosis of influenza are lacking. We validated nasopharyngeal (NP) flocked specimens in universal transport medium (UTM) and evaluated the clinical sensitivity and specificity of the Alere i influenza A&B test compared to those of the Xpert flu A/B assay. The Alere i influenza A&B test had an overall sensitivity and specificity of 93.8% and 62.5% for influenza A, respectively, and of 91.8% and 53.6% for influenza B, respectively. The poor specificity was due to influenza virus samples determined positive for both type A and B.Keywords
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