Endoscopic Resection of Hypothalamic Hamartoma Using a Novel Variable Aspiration Tissue Resector

Abstract

OBJECTIVE: We present a novel variable aspiration tissue resector for use with neuroendoscopy. METHODS: Two patients, 4 and 14 years old, respectively, presented with intractable gelastic seizures refractory to maximal medical therapies. Magnetic resonance imaging showed mass lesions of the third ventricle consistent with hypothalamic hamartoma. RESULTS: The patients underwent magnetic resonance imaging wand-guided endo-scopic resection of the tumor with the Suros novel variable aspiration tissue resector. There were no device-associated complications or adverse events. The hamartoma was disconnected in one patient, and gross total resection was achieved in the other. CONCLUSION: Endoscopy for tumor resection is still frustrated by the lack of surgical tools, such as ultrasonic aspirators, comparable with those available for use during open procedures. The variable-aspiration tissue resector reported here can be used to resect tumor tissue safely. These two cases demonstrate that gross total resection of small hypothalamic hamartomas is feasible with minimal morbidity through an endo-scopic approach.