PREOPERATIVE SENSORIMOTOR MAPPING IN BRAIN TUMOR PATIENTS USING SPONTANEOUS FLUCTUATIONS IN NEURONAL ACTIVITY IMAGED WITH FUNCTIONAL MAGNETIC RESONANCE IMAGING
- 1 December 2009
- journal article
- case report
- Published by Ovid Technologies (Wolters Kluwer Health) in Operative Neurosurgery
- Vol. 65 (6), ons226-ons236
- https://doi.org/10.1227/01.neu.0000350868.95634.ca
Abstract
To describe initial experience with resting-state correlation mapping as a potential aid for presurgical planning of brain tumor resection. Resting-state blood oxygenation-dependent functional magnetic resonance imaging (fMRI) scans were acquired in 17 healthy young adults and 4 patients with brain tumors invading sensorimotor cortex. Conventional fMRI motor mapping (finger-tapping protocol) was also performed in the patients. Intraoperatively, motor hand area was mapped using cortical stimulation. Robust and consistent delineation of sensorimotor cortex was obtained using the resting-state blood oxygenation-dependent data. Resting-state functional mapping localized sensorimotor areas consistent with cortical stimulation mapping and in all patients performed as well as or better than task-based fMRI. Resting-state correlation mapping is a promising tool for reliable functional localization of eloquent cortex. This method compares well with “gold standard” cortical stimulation mapping and offers several advantages compared with conventional motor mapping fMRI.Keywords
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