Pd(II)-Catalyzed para-Selective C–H Arylation of Monosubstituted Arenes
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- 11 August 2011
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 133 (35), 13864-13867
- https://doi.org/10.1021/ja206572w
Abstract
Pd-catalyzed highly para-selective C–H arylation of monosubstituted arenes (including toluene) is developed for the first time using an F+ reagent as a bystanding oxidant. This finding provides a new retrosynthetic disconnection for para-substituted biaryl synthesis via C–H/C–H cross-coupling.Keywords
This publication has 60 references indexed in Scilit:
- Bystanding F+ Oxidants Enable Selective Reductive Elimination from High‐Valent Metal Centers in CatalysisAngewandte Chemie, 2011
- Pd(II)-Catalyzed Carbonylation of C(sp3)−H Bonds: A New Entry to 1,4-Dicarbonyl CompoundsJournal of the American Chemical Society, 2010
- Regioselective Oxidative Arylation of Indoles Bearing N-Alkyl Protecting Groups: Dual C−H Functionalization via a Concerted Metalation−Deprotonation MechanismJournal of the American Chemical Society, 2010
- Ligand-Accelerated C−H Activation Reactions: Evidence for a Switch of MechanismJournal of the American Chemical Society, 2010
- Pd(II)-Catalyzed Olefination of sp3 C−H BondsJournal of the American Chemical Society, 2010
- Pd(0)/PR3-Catalyzed Intermolecular Arylation of sp3 C−H BondsJournal of the American Chemical Society, 2009
- Palladium(II)‐Catalyzed C-H Activation/C-C Cross‐Coupling Reactions: Versatility and PracticalityAngewandte Chemie, 2009
- Pd(II)-Catalyzed Olefination of Electron-Deficient Arenes Using 2,6-Dialkylpyridine LigandsJournal of the American Chemical Society, 2009
- Synthesis and Reactivity of a Mono-σ-Aryl Palladium(IV) Fluoride ComplexJournal of the American Chemical Society, 2009
- Oxidant-controlled regioselectivity in the oxidative arylation of N-acetylindolesTetrahedron Letters, 2008