Endobiliary radiofrequency ablation combined with bilateral metal stent placement for malignant hilar biliary obstruction
- 24 March 2020
- journal article
- research article
- Published by Georg Thieme Verlag KG in Endoscopy
- Vol. 52 (07), 595-599
- https://doi.org/10.1055/a-1133-4448
Abstract
Background The effectiveness of endobiliary radiofrequency ablation (RFA) is still uncertain, especially in patients with malignant hilar biliary obstruction (MHBO). We examined the efficacy of endobiliary RFA followed by bilateral self-expandable metal stent (SEMS) placement for unresectable MHBO. Methods 41 patients met the eligibility criteria for study inclusion. We evaluated the technical success, functional success, and recurrent biliary obstruction (RBO) associated with RFA with bilateral SEMS placement. Results The technical and functional success rates were both 95.1 % (39/41). The RBO rate was 38.5 % (15/39), and the median time to RBO was 230 days. Stricture length was positively correlated with time to RBO in the multivariate analysis (P = 0.03). The median time to RBO was significantly longer in patients with strictures > 15 mm in length than in those with strictures ≤ 15 mm (314 vs. 156 days; P = 0.02). Conclusions The present study showed that endobiliary RFA with bilateral SEMS placement achieved good results, but selection of patients with an appropriate stricture length may be needed to obtain a sufficient ablative effect.Keywords
This publication has 9 references indexed in Scilit:
- The safety of newly developed automatic temperature‐controlled endobiliary radiofrequency ablation system for malignant biliary strictures: A prospective multicenter studyJournal of Gastroenterology and Hepatology, 2019
- Endoscopic radiofrequency biliary ablation treatment: A comprehensive reviewDigestive Endoscopy, 2018
- Endoscopic biliary stenting: indications, choice of stents, and results: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline – Updated October 2017Endoscopy, 2018
- Radiofrequency ablation combined with biliary stent placement versus stent placement alone for malignant biliary strictures: a systematic review and meta-analysisGastrointestinal Endoscopy, 2018
- Efficacy and safety of endoscopic radiofrequency ablation for unresectable extrahepatic cholangiocarcinoma: a randomized trialEndoscopy, 2018
- Simultaneous Versus Sequential Side-by-Side Bilateral Metal Stent Placement for Malignant Hilar Biliary ObstructionsDigestive Diseases and Sciences, 2017
- Comparison of intraluminal radiofrequency ablation and stents versus stents alone in the management of malignant biliary obstructionInternational Journal of Hyperthermia, 2017
- TOKYO criteria 2014 for transpapillary biliary stentingDigestive Endoscopy, 2014
- Successful photodynamic therapy for nonresectable cholangiocarcinoma: a randomized prospective studyGastroenterology, 2003