Endoscopic radiofrequency biliary ablation treatment: A comprehensive review
- 16 November 2018
- journal article
- review article
- Published by Wiley in Digestive Endoscopy
- Vol. 31 (3), 245-255
- https://doi.org/10.1111/den.13298
Abstract
Radiofrequency ablation (RFA) acts by delivering thermal energy within the tissue, the result of a high‐frequency alternating current released from an active electrode, leading to coagulative necrosis and cellular death. Recently, a biliary catheter working on a guide‐wire has been developed and a number of studies have been performed so far. The present paper provides a comprehensive review of the literature on the results of the use of RFA for the clinical management of patients with unresectable malignant biliary strictures, benign biliary strictures, and residual adenomatous tissue in the bile duct after endoscopic papillectomy. The available data show that biliary RFA treatment is a promising adjuvant therapy in patients with unresectable malignant biliary obstruction. The procedure is safe, well tolerated and improves stent patency and survival, even though more studies are warranted. In patients with residual endobiliary adenomatous tissue after endoscopic papillectomy, a significant rate of neoplasia eradication after a single RFA session has been reported, thus favoring this treatment over surgical intervention. In these patients, as well as, in those with benign biliary strictures, dedicated probes with a short electrode able to focus the RF current on the short stenosis are needed to expand RFA treatment for these indications.Keywords
This publication has 48 references indexed in Scilit:
- A meta-analysis of long-term survival outcomes between surgical resection and radiofrequency ablation in patients with single hepatocellular carcinoma ≤ 2 cm (BCLC very early stage)International Journal of Surgery, 2018
- Which needle in the treatment of thyroid nodules?Gland Surgery, 2018
- Contrast-Enhanced Ultrasound-Guided Radiofrequency Ablation of Renal TumorsJournal of Kidney Cancer and VHL, 2018
- Radiofrecuencia pulmonar (parte 1): Estado actualRadiologia, 2015
- More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of CancerJournal of Immunology Research, 2011
- Evaluation of effects of a novel endoscopically applied radiofrequency ablation biliary catheter using an ex‐vivo pig liverJournal of Hepato-Biliary-Pancreatic Sciences, 2011
- The modern use of radiofrequency energy in surgery, endoscopy and interventional radiologyEuropean Surgery, 2008
- Image-guided radiofrequency ablation of renal cell carcinomaEuropean Radiology, 2006
- Activation of dendritic cells by local ablation of hepatocellular carcinomaJournal of Hepatology, 2005
- Study of Apoptosis and Heat Shock Protein (HSP) Expression in Hepatocytes Following Radiofrequency Ablation (RFA)Journal of Surgical Research, 2005