Multiple human beta interferon genes.
Open Access
- 1 September 1982
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 156 (3), 744-755
- https://doi.org/10.1084/jem.156.3.744
Abstract
Analysis of human .beta. interferon (IFN) mRNA preparations obtained from poly(I .cntdot. C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least 5 translationally active human IFN-.beta. mRNA species. The results obtained are consistent with the existence of IFN-.beta. genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed.This publication has 41 references indexed in Scilit:
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