Rational Confinement of Yttrium Vanadate within Three-Dimensional Graphene Aerogel: Electrochemical Analysis of Monoamine Neurotransmitter (Dopamine)
- 24 February 2021
- journal article
- research article
- Published by American Chemical Society (ACS) in ACS Applied Materials & Interfaces
- Vol. 13 (9), 10987-10995
- https://doi.org/10.1021/acsami.0c22781
Abstract
Real-time monitoring of neurotransmitter levels is of tremendous technological demand, which requires more sensitive and selective sensors over a dynamic concentration range. As a use case, we report yttrium vanadate within three-dimensional graphene aerogel (YVO/GA) as a novel electrocatalyst for detecting dopamine (DA). This synergy effect endows YVO/GA nanocomposite with good electrochemical behaviors for DA detection compared to other electrodes. Benefiting from tailorable properties, it provides a large specific surface area, rapid electron transfer, more active sites, good catalytic activity, synergic effect, and high conductivity. The essential analytical parameters were estimated from the calibration plot, such as a limit of detection (1.5 nM) and sensitivity (7.1 μA μM–1 cm–2) with the YVO/GA sensor probe electrochemical approach. The calibration curve was fitted with the correlation coefficient of 0.994 in the DA concentration range from 0.009 to 83 μM, which is denoted as the linear working range. We further demonstrate the proposed YVO/GA sensor’s applicability to detect DA in human serum sample with an acceptable recovery range. Our results imply that the developed sensor could be applied to the early analysis of dementia, psychiatric, and neurodegenerative disorders.Funding Information
- Ministry of Science and Technology of the People's Republic of China (107-2113-M-027-005-MY3)
- King Abdulaziz University (FP-79-42)
This publication has 69 references indexed in Scilit:
- Effect of the vanadium(v) concentration on the spectroscopic properties of nanosized europium-doped yttrium phosphatesDalton Transactions, 2012
- Mechanically strong and highly conductive graphene aerogel and its use as electrodes for electrochemical power sourcesJournal of Materials Chemistry, 2011
- Electrogenerated Chemiluminescence of Au Nanoclusters for the Detection of DopamineAnalytical Chemistry, 2011
- A Selective and Sensitive Method for Simultaneous Determination of Traces of Paracetamol and p‐Aminophenol in Pharmaceuticals Using Carbon Ionic Liquid ElectrodeElectroanalysis, 2008
- Rapid determination of acetaminophen and p-aminophenol in pharmaceutical formulations using miniaturized capillary electrophoresis with amperometric detectionAnalytica Chimica Acta, 2008
- Simultaneous voltammetric determination of dypirone and paracetamol with carbon paste electrode and multivariate calibration methodologyJournal of the Brazilian Chemical Society, 2008
- Paracetamol voltammetric microsensors based on electrocopolymerized–molecularly imprinted film modified carbon fiber microelectrodesThe Analyst, 2005
- Spectroscopic Properties of Neodymium-Doped Yttrium Orthovanadate Single Crystals with High-Resolution MeasurementJapanese Journal of Applied Physics, 2002
- Effect of temperature on excitation energy transfer and upconversion phenomena in Er:YVO4 single crystalsJournal of Alloys and Compounds, 2001
- Upconversion emission in -codoped crystalsPhysical Review B, 2000