Familial colorectal cancer syndromes: an overview of clinical management
- 16 March 2015
- journal article
- review article
- Published by Taylor & Francis Ltd in Expert Review of Gastroenterology & Hepatology
- Vol. 9 (6), 757-764
- https://doi.org/10.1586/17474124.2015.1026328
Abstract
Familial colorectal cancer syndromes pose a complex challenge to the treating clinician. Once a syndrome is recognized, genetic testing is often required to confirm the clinical suspicion. Management from that point is usually based on disease-specific guideline recommendations targeting risk reduction for the patient and their relatives through surgery, surveillance and chemoprophylaxis. The aim of this paper is to provide an up-to-date summary of the most common familial syndromes and their medical and surgical management, with specific emphasis on evidence-based interventions that improve patient outcome, and to present the information in a manner that is easily readable and clinically relevant to the treating clinician.This publication has 26 references indexed in Scilit:
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