In vitro activity of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin against Ghanaian isolates of Mycobacterium ulcerans
Open Access
- 1 February 2000
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 45 (2), 231-233
- https://doi.org/10.1093/jac/45.2.231
Abstract
MICs of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin were determined for 14 primary clinical isolates and three reference isolates of Mycobacterium ulcerans by modifying a standard agar dilution method for testing Mycobacterium tuberculosis sensitivity. All these antimicrobials were active against every isolate of M. ulcerans. Sparfloxacin exhibited the highest activity and ofloxacin was the least effective. Rifampicin exhibited the broadest range of activity.Keywords
This publication has 6 references indexed in Scilit:
- Mycobacterium ulcerans disease; Buruli ulcerTransactions of the Royal Society of Tropical Medicine and Hygiene, 1999
- In Vitro Susceptibility of Mycobacterium ulcerans to ClarithromycinAntimicrobial Agents and Chemotherapy, 1998
- Effectiveness of Excision of Pre-Ulcerative Buruli Lesions in Field Situations in a Rural District in GhanaTropical Doctor, 1998
- The Clinical Use of Fluoroquinolones for the Treatment of Mycobacterial DiseasesClinical Infectious Diseases, 1997
- A CONTROLLED TRIAL OF THE TREATMENT OF MYCOBACTERIUM ULCERANS INFECTION WITH CLOFAZIMINEThe Lancet, 1973
- Rifampicin In Experimental Mycobacterium Ulcerans InfectionJournal of Medical Microbiology, 1972