Comparison of Central Corneal Graft Thickness to Visual Acuity Outcomes in Endothelial Keratoplasty
- 1 April 2011
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Cornea
- Vol. 30 (4), 388-391
- https://doi.org/10.1097/ico.0b013e3181f236c6
Abstract
To evaluate visual acuity outcomes after endothelial keratoplasty (EK) and describe the relationship to postoperative central corneal graft thickness as measured by anterior segment optical coherence tomography (AS-OCT). A retrospective case series of 33 eyes in 28 patients undergoing routine EK using precut eye bank tissue was designed. All patients underwent serial central graft thickness measurements with AS-OCT. Based on the median central graft thickness of all patients, the eyes were divided into 2 groups: thin EK and thick EK. Differences between the groups were compared. The median postoperative graft thickness of all eyes was 131 μm. The eyes were divided into 2 groups based on this median: thin EK (graft thickness: ≤ 131 μm; range: 77-131 μm; average: 109 μm) and thick EK (graft thickness: > 131 μm; range: 138-182 μm; average: 162 μm). There was no statistically significant difference in age, sex, or preoperative best spectacle-corrected visual acuity (BSCVA) between the 2 groups. Average postoperative follow-up was 12.8 months. The thin EK group showed better postoperative BSCVA compared with the thick EK group (P < 0.01). All thin EK eyes had BSCVA greater than or equal to 20/25 with 71% of eyes achieving BSCVA of 20/20. In contrast, only 50% of thick EK eyes reached BSCVA greater than or equal to 20/25 with 19% obtaining BSCVA of 20/20. Thin EK versus thick EK, as measured by AS-OCT in the postoperative period, showed a statistically significant improvement in BSCVA.Keywords
This publication has 9 references indexed in Scilit:
- Retrospective Contralateral Study Comparing Descemet Stripping Automated Endothelial Keratoplasty With Penetrating KeratoplastyCornea, 2009
- Thickness Measurements of Donor Posterior Disks After Descemet Stripping Endothelial Keratoplasty With Anterior Segment Optical Coherence TomographyCornea, 2009
- Precut Tissue for Descemet's Stripping Automated Endothelial Keratoplasty: Vision, Astigmatism, and Endothelial SurvivalOphthalmology, 2009
- Endothelial Keratoplasty: The Influence of Insertion Techniques and Incision Size on Donor Endothelial SurvivalCornea, 2009
- Agreement among 3 Methods to Measure Corneal Thickness: Ultrasound Pachymetry, Orbscan II, and Visante Anterior Segment Optical Coherence TomographyOphthalmology, 2007
- Assessment and reproducibility of anterior chamber depth measurement with anterior segment optical coherence tomography compared with immersion ultrasonographyJournal of Cataract & Refractive Surgery, 2007
- Descemet’s Stripping with Endothelial Keratoplasty: Comparative Outcomes with Microkeratome-Dissected and Manually Dissected Donor TissueOphthalmology, 2006
- Sutureless, Posterior Lamellar KeratoplastyCornea, 2002
- A Surgical Technique for Posterior Lamellar KeratoplastyCornea, 1998