Mitochondrial DNA and the origins of the domestic horse
Open Access
- 18 July 2002
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences of the United States of America
- Vol. 99 (16), 10905-10910
- https://doi.org/10.1073/pnas.152330099
Abstract
The place and date of the domestication of the horse has long been a matter for debate among archaeologists. To determine whether horses were domesticated from one or several ancestral horse populations, we sequenced the mitochondrial D-loop for 318 horses from 25 oriental and European breeds, including American mustangs. Adding these sequences to previously published data, the total comes to 652, the largest currently available database. From these sequences, a phylogenetic network was constructed that showed that most of the 93 different mitochondrial (mt)DNA types grouped into 17 distinct phylogenetic clusters. Several of the clusters correspond to breeds and/or geographic areas, notably cluster A2, which is specific to Przewalski's horses, cluster C1, which is distinctive for northern European ponies, and cluster D1, which is well represented in Iberian and northwest African breeds. A consideration of the horse mtDNA mutation rate together with the archaeological timeframe for domestication requires at least 77 successfully breeding mares recruited from the wild. The extensive genetic diversity of these 77 ancestral mares leads us to conclude that several distinct horse populations were involved in the domestication of the horse.This publication has 22 references indexed in Scilit:
- Widespread Origins of Domestic Horse LineagesScience, 2001
- mtDNA Variation among Greenland Eskimos: The Edge of the Beringian ExpansionAmerican Journal of Human Genetics, 2000
- Extant and fossil Equus (Mammalia, Perissodactyla) skulls: a morphometric definition of the subgenus EquusZoologica Scripta, 2000
- A pedigree‐based study of mitochondrial d‐loop DNA sequence variation among Arabian horsesAnimal Genetics, 2000
- Phylogenetic relationships of Cheju horses to other horse breeds as determined by mtDNA D-loop sequence polymorphismAnimal Genetics, 1999
- Botai and the Origins of Horse DomesticationJournal of Anthropological Archaeology, 1999
- DiscussionQuaternary Science Reviews, 1998
- Synchronized Terrestrial Atmospheric Deglacial Records Around the North AtlanticScience, 1996
- The complete mitochondrial DNA sequence of the horse, Equus caballus: extensive heteroplasmy of the control regionGene, 1994
- Polymorphic sequence in the D‐loop region of equine mitochondrial DNAAnimal Genetics, 1994