Review: Capripoxvirus Diseases: Current Status and Opportunities for Control
Top Cited Papers
Open Access
- 13 November 2015
- journal article
- review article
- Published by Hindawi Limited in Transboundary and Emerging Diseases
- Vol. 64 (3), 729-745
- https://doi.org/10.1111/tbed.12444
Abstract
Lumpy skin disease, sheeppox and goatpox are high-impact diseases of domestic ruminants with a devastating effect on cattle, sheep and goat farming industries in endemic regions. In this article, we review the current geographical distribution, economic impact of an outbreak, epidemiology, transmission and immunity of capripoxvirus. The special focus of the article is to scrutinize the use of currently available vaccines to investigate the resource needs and challenges that will have to be overcome to improve disease control and eradication, and progress on the development of safer and more effective vaccines. In addition, field evaluation of the efficacy of the vaccines and the genomic database available for poxviruses are discussed.Keywords
Funding Information
- Bill and Melinda Gates Foundation (OPP1126866)
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