A case of successful treatment of cutaneous Acanthamoeba infection in a lung transplant recipient
- 21 February 2007
- journal article
- case report
- Published by Wiley in Transplant Infectious Disease
- Vol. 9 (1), 51-54
- https://doi.org/10.1111/j.1399-3062.2006.00159.x
Abstract
Acanthamoeba species are known to cause 2 well-described entities: (1) granulomatous amoebic encephalitis (GAE), which usually affects immunocompromised hosts, and (2) keratitis, which typically follows trauma associated with contamination of water or contact lenses. Less common manifestations include pneumonitis and a subacute granulomatous dermatitis. We describe a case of granulomatous dermatitis secondary to Acanthamoeba infection in a lung transplant recipient and a successful outcome following treatment with lipid formulation of amphotericin B and voriconazole. We believe this is the second case report describing disseminated Acanthamoeba infection in a lung transplant recipient. We also describe successful outcome with a combination of lipid formulation of amphotericin B and voriconazole, drugs that have not been previously reported to treat Acanthamoeba.Keywords
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