Natural History of Rheumatic Aortic Regurgitation
- 1 September 1971
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 44 (3), 368-380
- https://doi.org/10.1161/01.cir.44.3.368
Abstract
The medical courses of 174 young patients with aortic regurgitation were followed prospectively for a median of 10 years. The data were analyzed by life-table methods; congestive failure and angina, as well as death, were considered as end points, since the occurrence of the former is considered sufficient indication for aortic valve replacement. Thirty-one patients developed the triad of moderate or marked left ventricular enlargement, two or three electrocardiographic abnormalities, and abnormal blood pressure. Thirty-three percent of these patients either died or had failure or angina within 1 year, 48% within 2 years, 65% within 3 years, and 87% within 6 years from the acquisition of the triad. The 71 patients with none of the above features had uneventful courses. Of the 71 patients with one or two features only seven either died (three) or became symptomatic. These data are useful for patient selection for surgery before symptoms appear.This publication has 6 references indexed in Scilit:
- Prosthetic replacement of cardiac valves: Five and one-half years' experienceThe American Journal of Cardiology, 1969
- The Aortic ValveAnnual Review of Medicine, 1965
- Rheumatic Fever in Children and Adolescents: A Long-term Epidemiologic Study of Subsequent Prophylaxis, Streptococcal Infections, and Clinical Sequelae: VII. Cardiac Changes and SequelaeAnnals of Internal Medicine, 1964
- Maximum utilization of the life table method in analyzing survivalJournal of Chronic Diseases, 1958
- A clinical study of one hundred cases of severe aortic insufficiencyAmerican Journal Of Medicine, 1956