Microbial Exposure in Infancy and Subsequent Appearance of Type 1 Diabetes Mellitus–Associated Autoantibodies
Open Access
- 1 August 2014
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Pediatrics
- Vol. 168 (8), 755-763
- https://doi.org/10.1001/jamapediatrics.2014.296
Abstract
The hygiene hypothesis that microbial exposure during early life may affect susceptibility to the development of allergic diseases1 has been extended to investigate whether the hypothesis is true for autoimmune diseases, such as type 1 diabetes.2 Decreased environmental biodiversity through influence on human microbiota and its immunologic actions was recently implicated3 in the occurrence of atopic and other chronic inflammatory diseases.This publication has 28 references indexed in Scilit:
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