Male germ cell transplantation in rats: apparent synchronization of spermatogenesis between host and donor seminiferous epithelia
- 1 December 1995
- journal article
- Published by Wiley in International Journal of Andrology
- Vol. 18 (6), 326-330
- https://doi.org/10.1111/j.1365-2605.1995.tb00570.x
Abstract
Primordial germ cells (PGC) and gonocytes from male Sprague-Dawley rat fetuses and neonates were transplanted via the rete testis into the lumen of the seminiferous tubules of recipient adult Long Evans rats. The donor germ cells apparently differentiated into mini-tubules or irregular segments of seminiferous epithelium within the lumen of the host seminiferous tubules, and exhibited qualitatively normal spermatogenesis in 10 out of 16 recipients. The stage of spermatogenesis of the intraluminal epithelium was synchronized closely with that of the adjacent seminiferous tubule epithelium, suggesting that the spermatogenic cycle is regulated locally by the intraluminal microenvironment. Male germ cell transplantation provides an interesting new tool for investigating the control of spermatogenesis.Keywords
This publication has 12 references indexed in Scilit:
- Germline transmission of donor haplotype following spermatogonial transplantation.Proceedings of the National Academy of Sciences of the United States of America, 1994
- Spermatogenesis following male germ-cell transplantation.Proceedings of the National Academy of Sciences of the United States of America, 1994
- The Sertoli-Germ Cell Communication Network in MammalsInternational Review of Cytology, 1993
- Quantitative analysis of germ cell numbers and relation to intratesticular testosterone following vitamin A-induced synchronization of spermatogenesis in the ratJournal of Endocrinology, 1989
- Isolation and Biochemical Studies of Enriched Populations of Spermatogonia and Early Primary Spermatocytes from Rat Testes1Biology of Reproduction, 1986
- Isolation of mouse primordial germ cellsExperimental Cell Research, 1982
- The mammalian rete testis — a morphological examinationThe Anatomical Record, 1976
- TESTOSTERONE CONCENTRATION IN THE FLUIDS OF SEMINIFEROUS TUBULES, THE INTERSTITIUM AND THE RETE TESTIS OF THE RATJournal of Endocrinology, 1976
- ANTIFERTILITY SUBSTANCES AND THEIR ASSESSMENT IN THE MALE RODENTReproduction, 1961
- DEFINITION OF THE STAGES OF THE CYCLE OF THE SEMINIFEROUS EPITHELIUM IN THE RATAnnals of the New York Academy of Sciences, 1952