Impact of delivery mode and gestational age on haematological parameters in Taiwanese preterm infants
- 29 June 2009
- journal article
- Published by Wiley in Journal of Paediatrics and Child Health
- Vol. 45 (6), 332-336
- https://doi.org/10.1111/j.1440-1754.2009.01497.x
Abstract
Aim: Reference ranges of haematological parameters in preterm infants are limited. The aim of this study is to determine the reference values of haematological parameters in preterm infants in Taiwan, and to assess the impact of gestational age and mode of delivery on these parameters. Method: Medical records were retrospectively reviewed in preterm infants admitted to National Taiwan University Hospital from January 2001 to December 2004. The inclusion criteria included infants with <37 weeks of gestation who had blood sampling within 24 h of birth. The exclusion criteria included those with maternal history of antepartum haemorrhage, chorioamnionitis, fever, sepsis, preeclampsia and hypertension; and perinatal history of twin‐to‐twin transfusion syndrome, feto‐maternal transfusion, injury and infection. Results: Of 568 preterm infants with blood cell counts, 337 were available for analysis. There were trends of increase in red blood cell counts, haemoglobin levels and haematocrit values as gestation increased up to 34 weeks. In contrast, a trend of decrease was noted in mean corpuscular volume values. There was an initial trend of decrease in white blood cell counts and then increased after 31 weeks gestation. The platelet counts were essentially unchanged. Infants born by vaginal delivery generally had higher haematological parameters than those born by Caesarean section at different gestational ages except for mean corpuscular volume values. Conclusions: We established the reference ranges of haematological parameters in Taiwanese preterm infants. Health‐care professionals must be cautious in clinical application of the haematological values because of varying antenatal and perinatal risk factors.Keywords
This publication has 16 references indexed in Scilit:
- Randomized Trial of Liberal Versus Restrictive Guidelines for Red Blood Cell Transfusion in Preterm InfantsPediatrics, 2005
- Labor Does Not Affect the Neonatal Absolute Nucleated Red Blood Cell CountAmerican Journal of Perinatology, 2003
- Red blood cell transfusions in very and extremely low birthweight infants under restrictive transfusion guidelines: is exogenous erythropoietin necessary?Archives of Disease in Childhood: Fetal & Neonatal, 2001
- MODE OF DELIVERY AND NEONATAL HEMATOCRITAmerican Journal of Perinatology, 2000
- Venous and Arterial Hematologic Profiles of Very Low Birth Weight InfantsPEDIATRICS, 2000
- Percentile Curves for Various Hematologic Measurements at Birth in Arab Preterm Babies of Different Gestational AgesArchives of Pediatrics & Adolescent Medicine, 1991
- Early diagnosis of neonatal sepsis using a hematologic scoring systemThe Journal of Pediatrics, 1988
- Frequency and mechanism of neonatal thrombocytopeniaThe Journal of Pediatrics, 1986
- Red cell values on the first postnatal day during the last 16 weeks of gestationAmerican Journal of Hematology, 1976
- EFFECT OF GRAVITY ON PLACENTAL TRANSFUSIONThe Lancet, 1969