Effects of different levels of physical inactivity on plasma visfatin in healthy normal-weight men
- 1 June 2013
- journal article
- research article
- Published by Canadian Science Publishing in Applied Physiology, Nutrition, and Metabolism
- Vol. 38 (6), 689-693
- https://doi.org/10.1139/apnm-2012-0434
Abstract
We tested whether physical inactivity (PI) is an independent predictor of plasma visfatin, a newly discovered adipokine likely involved in the relationship between obesity-associated low-grade inflammation and insulin resistance. PI was induced in healthy men (Body Mass Index = 23.4 ± 0.6 kg·m−2) by 10 days of confinement (n = 8), 1 month of detraining (n = 10), and 3 months of bed rest with (n = 7) and without exercise (n = 8). Visfatin was negatively associated with activity energy expenditure (p = 0.03). No relationship was observed with insulin sensitivity. This suggested that PI itself increases visfatin concentrations.Keywords
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