Inhibition of bacterial adhesion by tobramycinimpregnated PMMA bone cement
- 1 January 1992
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Orthopaedica
- Vol. 63 (3), 301-304
- https://doi.org/10.3109/17453679209154787
Abstract
We investigated the effect of tobramycin-impregnated polymethylmethacrylate (PMMA) bone cement on the adhesion and colonization of Staphylococcus epidermidis. The pattern of colonization was quanti-tated using plate count techniques and electron microscopy. Colonization of the tobramycin-impregnated disc surface by adhesive bacteria was demonstrated but it was less than in the control disc. This finding suggests that tobramycin may reduce bacterial adherence and proliferation on the PMMA surface.Keywords
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