M&S Smart System Contrast Sensitivity Measurements Compared With Standard Visual Function Measurements in Primary Open-Angle Glaucoma Patients
- 1 June 2017
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Glaucoma
- Vol. 26 (6), 528-533
- https://doi.org/10.1097/ijg.0000000000000659
Abstract
Purpose: To evaluate the nature and extent of letter contrast sensitivity (CS) deficits in glaucoma patients using a commercially available computer-based system (M&S Smart System II) and to compare the letter CS measurements to standard clinical measures of visual function. Methods: Ninety-four subjects with primary open-angle glaucoma participated. Each subject underwent visual acuity, letter CS, and standard automated perimetry testing (Humphrey SITA 24-2). All subjects had a best-corrected visual acuity (BCVA) of 0.3 log MAR (20/40 Snellen equivalent) or better and reliable standard automated perimetry (fixation losses, false positives, and false negatives r=0.51, Pr=−0.22, P=0.03), but not with HVF MD (r=−0.12, P=0.26). A subset of the subject sample (∼20%) had moderate to no field loss (≤−6 dB MD) and minimal to no BCVA loss (≤0.3 log MAR), but had poor letter CS. AUCSF was correlated significantly with HVF MD (r=0.46, P<0.001). Conclusions: The present study is the first to evaluate letter CS in glaucoma using the digital M&S Smart System II display. Letter CS correlated significantly with standard HVF MD measurements, suggesting that letter CS may provide a useful adjunct test of visual function for glaucoma patients. In addition, the significant correlation between HVF MD and the combined index of CS and BCVA (AUCSF) suggests that this measure may also be useful for quantifying visual dysfunction in glaucoma patients.Keywords
This publication has 22 references indexed in Scilit:
- Measuring Contrast Sensitivity Using the M&S Smart System II versus the Pelli-Robson ChartOphthalmology, 2013
- Driving performance in patients with mild to moderate glaucomatous clinical vision changes.2007
- The number of people with glaucoma worldwide in 2010 and 2020British Journal of Ophthalmology, 2006
- Contrast sensitivityOphthalmology Clinics of North America, 2003
- Comparison of Contrast Sensitivity, Visual Acuity, and Humphrey Visual Field Testing in Patients with GlaucomaJournal of Glaucoma, 2003
- Glaucoma Patients' Assessment of Their Visual Function and Quality of LifeJournal of Glaucoma, 2002
- Correlation of Visual Field With Quality-of-Life Measures at Diagnosis in the Collaborative Initial Glaucoma Treatment Study (CIGTS)Journal of Glaucoma, 2001
- The impact of glaucoma on the quality of life of patients in NorwayActa Ophthalmologica Scandinavica, 2001
- Electrophysiological evidence that early glaucoma affects foveal visionDocumenta Ophthalmologica, 1987
- A simple grating test for contrast sensitivity: preliminary results indicate value in screening for glaucoma.1978