European Respiratory Society guidelines for the management of adult bronchiectasis
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Open Access
- 9 September 2017
- journal article
- practice guideline
- Published by European Respiratory Society (ERS) in European Respiratory Journal
- Vol. 50 (3), 1700629
- https://doi.org/10.1183/13993003.00629-2017
Abstract
Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines. The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature. A multidisciplinary group representing respiratory medicine, microbiology, physiotherapy, thoracic surgery, primary care, methodology and patients considered the most relevant clinical questions (for both clinicians and patients) related to management of bronchiectasis. Nine key clinical questions were generated and a systematic review was conducted to identify published systematic reviews, randomised clinical trials and observational studies that answered these questions. We used the GRADE approach to define the quality of the evidence and the level of recommendations. The resulting guideline addresses the investigation of underlying causes of bronchiectasis, treatment of exacerbations, pathogen eradication, long term antibiotic treatment, anti-inflammatories, mucoactive drugs, bronchodilators, surgical treatment and respiratory physiotherapy. These recommendations can be used to benchmark quality of care for people with bronchiectasis across Europe and to improve outcomes.Keywords
Funding Information
- European Respiratory Society (Task force)
This publication has 99 references indexed in Scilit:
- Effects of long‐term azithromycin therapy on airway oxidative stress markers in non‐cystic fibrosis bronchiectasisRespirology, 2013
- Mechanisms of immune dysfunction and bacterial persistence in non-cystic fibrosis bronchiectasisMolecular Immunology, 2013
- Bronchiectasis-Associated Hospitalizations in Germany, 2005–2011: A Population-Based Study of Disease Burden and TrendsPLOS ONE, 2013
- GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendationsJournal of Clinical Epidemiology, 2013
- Effectiveness of treatment with high-frequency chest wall oscillation in patients with bronchiectasisBMC Pulmonary Medicine, 2013
- Self-Paced Walking within a Diverse Topographical Environment Elicits an Appropriate Training Stimulus for Cardiac Rehabilitation PatientsRehabilitation Research and Practice, 2012
- Risk factors for morbidity and death in non-cystic fibrosis bronchiectasis: a retrospective cross-sectional analysis of CT diagnosed bronchiectatic patientsRespiratory Research, 2012
- Quality of life and dyspnoea in patients treated with bosentan for idiopathic pulmonary fibrosis (BUILD-1)European Respiratory Journal, 2009
- A 4-Year Trial of Tiotropium in Chronic Obstructive Pulmonary DiseaseThe New England Journal of Medicine, 2008
- Prevalence and Economic Burden of BronchiectasisClinical Pulmonary Medicine, 2005