DETERMINATION OF FAT TOLERANCE IN PATIENTS WITH MYOCARDIAL INFARCTION

Abstract

In recent years attention has been focused on the possibility that the physical state and particle size of the serum lipids rather than their chemical properties may be etiologically significant in atherosclerosis. Studies utilizing such diverse techniques as chylomicron counts,¹nephelometry,²or ultracentrifugation³suggest that comparatively large lipid or lipoprotein particles suspended in the blood may be related to the presence of atherosclerosis. However, these methods of study, although of great value in the investigation of the problem, are not readily applicable as routine procedures in the clinical laboratory, since they entail the use of involved techniques or special apparatus. The measurement of serum turbidity in an ordinary photoelectric colorimeter is a simple, reliable, rapid, and inexpensive method of determining the presence of macromolecular particles suspended in the blood. Particles with diameters more than one-quarter of the wave length of visible light (or 0.1 μ) deflect and