Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling
Open Access
- 11 March 2011
- journal article
- research article
- Published by Springer Science and Business Media LLC in Cellular Oncology
- Vol. 34 (2), 141-153
- https://doi.org/10.1007/s13402-011-0019-7
Abstract
Mantle cell lymphoma (MCL) is currently an incurable entity, and new therapeutic approaches are needed. We have applied a high-throughput phospho-proteomic technique to MCL cell lines to identify activated pathways and we have then validated our data in both cell lines and tumor tissues.Keywords
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