General-Purpose Genotype or How Epigenetics Extend the Flexibility of a Genotype
Open Access
- 15 December 2011
- journal article
- research article
- Published by Hindawi Limited in Genetics Research International
- Vol. 2012, 1-7
- https://doi.org/10.1155/2012/317175
Abstract
This project aims at investigating the link between individual epigenetic variability (not related to genetic variability) and the variation of natural environmental conditions. We studied DNA methylation polymorphisms of individuals belonging to a single genetic lineage of the clonal diploid fish Chrosomus eos-neogaeus sampled in seven geographically distant lakes. In spite of a low number of informative fragments obtained from an MSAP analysis, individuals of a given lake are epigenetically similar, and methylation profiles allow the clustering of individuals in two distinct groups of populations among lakes. More importantly, we observed a significant pH variation that is consistent with the two epigenetic groups. It thus seems that the genotype studied has the potential to respond differentially via epigenetic modifications under variable environmental conditions, making epigenetic processes a relevant molecular mechanism contributing to phenotypic plasticity over variable environments in accordance with the GPG model.Keywords
Funding Information
- Natural Sciences and Engineering Research Council of Canada
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