The Inverse Relation between Fish Consumption and 20-Year Mortality from Coronary Heart Disease
- 9 May 1985
- journal article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 312 (19), 1205-1209
- https://doi.org/10.1056/nejm198505093121901
Abstract
The low death rate from coronary heart disease among the Greenland Eskimos has been ascribed to their high fish consumption. We therefore decided to investigate the relation between fish consumption and coronary heart disease in a group of men in the town of Zutphen, the Netherlands. Information about the fish consumption of 852 middle-aged men without coronary heart disease was collected in 1960 by a careful dietary history obtained from the participants and their wives. During 20 years of follow-up 78 men died from coronary heart disease. An inverse dose-response relation was observed between fish consumption in 1960 and death from coronary heart disease during 20 years of follow-up. This relation persisted after multiple logistic-regression analyses. Mortality from coronary heart disease was more than 50 per cent lower among those who consumed at least 30 g of fish per day than among those who did not eat fish. We conclude that the consumption of as little as one or two fish dishes per week may be of preventive value in relation to coronary heart disease.Keywords
This publication has 25 references indexed in Scilit:
- Thromboxane A3 (TXA3) is formed in human platelets after dietary eicosapentaenoic acid (C20:5ω3)Biochemical and Biophysical Research Communications, 1983
- n-3 POLYUNSATURATED FATTY ACIDS AND ISCHAEMIC HEART DISEASEThe Lancet, 1982
- EFFECTS OF 11-WEEK INCREASE IN DIETARY EICOSAPENTAENOIC ACID ON BLEEDING TIME, LIPIDS, AND PLATELET AGGREGATIONThe Lancet, 1981
- EICOSAPENTAENOIC ACID AND PLATELET FUNCTION IN TAPANESEThe Lancet, 1980
- Epidemiology as a Guide to Clinical DecisionsThe New England Journal of Medicine, 1980
- COD-LIVER OIL, PLATELET FATTY ACIDS, AND BLEEDING TIMEThe Lancet, 1980
- FISH OILS, PROSTAGLANDINS, AND ARTERIAL THROMBOSISThe Lancet, 1979
- EICOSAPENTAENOIC ACID AND PREVENTION OF THROMBOSIS AND ATHEROSCLEROSIS?The Lancet, 1978
- PLASMA LIPID AND LIPOPROTEIN PATTERN IN GREENLANDIC WEST-COAST ESKIMOSThe Lancet, 1971
- Human Atherosclerosis and the DietCirculation, 1952