Renal candidiasis in neonates with candiduria
- 1 November 1999
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in The Pediatric Infectious Disease Journal
- Vol. 18 (11), 959-963
- https://doi.org/10.1097/00006454-199911000-00004
Abstract
Candida species commonly cause urinary tract infection in infants admitted to neonatal intensive care units. The purpose of this study was to describe the natural history of renal candidiasis as evidenced by sonography in infants with candiduria. The medical records of all infants who developed candiduria during their neonatal intensive care hospitalization between 1982 and 1993 were reviewed. Candiduria was defined as the isolation of Candida from (1) one or more specimens obtained by bladder catheterization or suprapubic aspiration, (2) one or more voided specimens and concurrent positive cultures from another sterile body site or (3) one or more voided specimens and changes on renal ultrasound consistent with renal candidiasis. Renal ultrasounds were retrospectively reviewed by one pediatric radiologist. Nonshadowing echogenic foci were considered evidence of renal fungus balls. Forty-one infants with candiduria were identified. Thirty-six infants underwent 1 or more renal imaging studies (ultrasonography, 35; computerized tomography, 1). The incidence of renal candidiasis in neonates with candiduria, defined as renal fungus balls or renal fungal abscess, was 42%. Of the 13 patients who had sonographic abnormalities suggestive of renal fungus balls, 7 had abnormalities on the first ultrasound obtained after the discovery of candiduria, whereas 6 patients developed abnormalities between 8 and 39 days later. Serial renal ultrasounds are required to reliably detect late appearing renal fungus balls in neonates with candiduria. Complications requiring surgical intervention, like urinary tract obstruction, were uncommon.Keywords
This publication has 21 references indexed in Scilit:
- Prevalence of Candida species in hospital-acquired urinary tract infections in a neonatal intensive care unitThe Pediatric Infectious Disease Journal, 1997
- Urinary tract candidiasis in neonates and infantsBritish Journal of Urology, 1995
- Acute renal failure in a neonate due to pelviureteric candidal bezoars successfully treated with long‐term systemic fluconazoleActa Paediatrica, 1992
- Neonatal renal candidal bezoar.Archives of Disease in Childhood, 1992
- Percutaneous nephrostomy drainage in the management of neonatal anuria secondary to renal candidiasisJournal of Pediatric Surgery, 1990
- An assessment of sonography in the diagnosis and management of neonatal renal candidiasisClinical Radiology, 1989
- The Management of Obstructive Renal Candidiasis in the NeonateBritish Journal of Urology, 1987
- Renal candidiasis of the infant: Ultrasound evaluationUrologic Radiology, 1986
- Anuria in a premature infant due to ureteropelvic fungal bezoarsEuropean Journal of Pediatrics, 1986
- Ultrasound in the diagnosis of systemic candidiasis (renal and cranial) in very low birth weight premature infantsPediatric Radiology, 1986