Simultaneous Determination of Perfluorinated Compounds in Edible Oil by Gel-Permeation Chromatography Combined with Dispersive Solid-Phase Extraction and Liquid Chromatography–Tandem Mass Spectrometry
- 22 September 2015
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Agricultural and Food Chemistry
- Vol. 63 (38), 8364-8371
- https://doi.org/10.1021/acs.jafc.5b03903
Abstract
A simple analytical method was developed for the simultaneous analysis of 18 perfluorinated compounds (PFCs) in edible oil. The target compounds were extracted by acetonitrile, purified by gel permeation chromatography (GPC) and dispersive solid-phase extraction (DSPE) using graphitized carbon black (GCB) and octadecyl (C18), and analyzed by liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ES-MS/MS) in negative ion mode. Recovery studies were performed at three fortification levels. The average recoveries of all target PFCs ranged from 60 to 129%, with an acceptable relative standard deviation (RSD) (1-20%, n = 3). The method detection limits (MDLs) ranged from 0.004 to 0.4 μg/kg, which was significantly improved compared with the existing liquid-liquid extraction and cleanup method. The method was successfully applied for the analysis of all target PFCs in edible oil samples collected from markets in Beijing, China, and the results revealed that C6-C10 perfluorocarboxylic acid (PFCAs) and C7 perfluorosulfonic acid PFSAs were the major PFCs detected in oil samples.Funding Information
- Ministry of Science and Technology of the People's Republic of China (2012BAD29B03)
This publication has 48 references indexed in Scilit:
- Monitoring of Perfluorinated Compounds in Aquatic Biota: An Updated ReviewEnvironmental Science & Technology, 2011
- Tissue Distribution and Maternal Transfer of Poly- and Perfluorinated Compounds in Chinese Sturgeon (Acipenser sinensis): Implications for Reproductive RiskEnvironmental Science & Technology, 2010
- Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of ActionToxicological Sciences, 2007
- Perfluoroalkyl Acids: A Review of Monitoring and Toxicological FindingsToxicological Sciences, 2007
- Perfluoroalkyl Contaminants in the Canadian Arctic: Evidence of Atmospheric Transport and Local ContaminationEnvironmental Science & Technology, 2007
- Particle Size Distribution and Respiratory Deposition Estimates of Airborne Perfluorooctanoate and Perfluorooctanesulfonate in Kyoto Area, JapanBulletin of Environmental Contamination and Toxicology, 2006
- Quantitative Determination of Fluorinated Alkyl Substances by Large-Volume-Injection Liquid Chromatography Tandem Mass SpectrometryCharacterization of Municipal WastewatersEnvironmental Science & Technology, 2005
- Quantitative Determination of Perfluorochemicals in Sediments and Domestic SludgeEnvironmental Science & Technology, 2005
- Analysis of Perfluorinated Acids at Parts-Per-Quadrillion Levels in Seawater Using Liquid Chromatography-Tandem Mass SpectrometryEnvironmental Science & Technology, 2004
- The Toxicology of PerfluorooctanoateCritical Reviews in Toxicology, 2004