Positron Emission Tomography in the Diagnosis and Staging of Urinary Bladder Cancer
- 1 January 1996
- journal article
- research article
- Published by SAGE Publications in Acta Radiologica
- Vol. 37 (2), 180-185
- https://doi.org/10.1177/02841851960371p137
Abstract
Purpose: : Evaluation of positron emission tomography (PET) using 18F-2-fluoro-2-deoxy-d-glucose (18FDG) and l-methyl-11C-methionine in the diagnosis and staging of urinary bladder carcinoma. Material and Methods: : Twenty-three patients with biopsy-proven urinary bladder carcinoma were examined with PET after intravenous injection of 11C-methionine; 2 were also examined with 18FDG. The results from the PET investigations were compared with CT or MR findings and TNM classification before and after treatment. Results: : The urinary excretion of 18FDG prevented distinction of the primary tumour from the surrounding tracer. With 11C-methionine it was possible to detect 18/23 primary tumours. A trend was seen, suggesting that the higher the uptake values of 11C-methionine in the tumour, the greater the tumour stage. Conclusion: : It is possible to visualize urinary bladder tumours larger than 1 cm in diameter with PET using 11C-methionine, but the value of the method in the staging of the lesions is not superior to conventional methods.Keywords
This publication has 9 references indexed in Scilit:
- Positron emission tomography with L‐methyl‐11 C‐methionine in the monitoring of therapy response in muscle‐invasive transitional cell carcinoma of the urinary bladderBritish Journal of Urology, 1994
- Increasing survival of patients with urinary bladder cancer. A nationwide study in sweden 1960–1986European Journal of Cancer, 1993
- Bladder tumor staging: comparison of conventional and gadolinium-enhanced dynamic MR imaging and CT.Radiology, 1992
- [C11]Methionine Quantitation in Cancer PET StudiesJournal of Computer Assisted Tomography, 1992
- Recurrent rectal cancer and scar: differentiation with PET and MR imaging.Radiology, 1992
- Uptake of 2-Deoxy, 2-(18F) Fluoro-D-Glucose in Bladder Cancer: Animal Localization and Initial Patient Positron Emission TomographyJournal of Urology, 1991
- Performance Characteristics of an Eight-Ring Whole Body PET ScannerJournal of Computer Assisted Tomography, 1990
- Bladder cancer: staging with CT and MR imaging.Radiology, 1989
- Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake DataJournal of Cerebral Blood Flow & Metabolism, 1983