Transvaginal ultrasound and diagnostic hysteroscopy as a predictor of endometrial polyps: risk factors for premalignancy and malignancy
- 1 March 2005
- journal article
- research article
- Published by BMJ in International Journal of Gynecologic Cancer
- Vol. 15 (2), 325-328
- https://doi.org/10.1111/j.1525-1438.2005.15224.x
Abstract
The aim of this study is to assess accuracy of transvaginal ultrasound (TVUS) and diagnostic hysteroscopy in diagnosing endometrial polyps and to determine premalignancy and malignancy rates in asymptomatic women. The study was designed to retrospectively analyze 438 women who underwent operative hysteroscopy in a day-care unit when endometrial polyp was suspected after TVUS and diagnostic hysteroscopy. Multivariate logistic regression modeling showed effects of age, previous breast cancer with tamoxifen treatment, and menopause with or without bleeding on pathologic results. The results indicate that positive predictive value of TVUS with diagnostic hysteroscopy was 79.9%. Premalignancy or malignancy occurred in 3.2% and was significantly related to menopause with abnormal bleeding (P < 0.001), which carried a 20-fold higher risk of pathology than any other group. Age was also a risk factor. It was concluded that TVUS with diagnostic hysteroscopy reliably evaluates endometrial polyps. The low incidence of endometrial tumors in asymptomatic (especially premenopausal) women suggests that their operative evaluation may not be cost effective. Larger studies are needed to support this tentative conclusion.Keywords
This publication has 15 references indexed in Scilit:
- Comparison of hydrosonography and transvaginal ultrasonography in the detection of intracavitary pathologies in women with abnormal uterine bleedingInternational Journal of Gynecologic Cancer, 2004
- Diagnostic hysteroscopy: a valuable diagnostic tool in the diagnosis of structural intra-cavital pathology and endometrial hyperplasia or carcinoma?: Six years of experience with non-clinical diagnostic hysteroscopyEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, 2003
- The risk of premalignant and malignant pathology in endometrial polypsActa Obstetricia et Gynecologica Scandinavica, 2002
- Dilatation and curettage fails to detect most focal lesions in the uterine cavity in women with postmenopausal bleedingActa Obstetricia et Gynecologica Scandinavica, 2001
- Complications of hysteroscopyGynaecological Endoscopy, 2001
- The risk of premalignant and malignant pathology in endometrial polypsActa Obstetricia et Gynecologica Scandinavica, 2000
- Endometrial polyps during menopause, characterization and significanceActa Obstetricia et Gynecologica Scandinavica, 1999
- Which endometrial polyps should be resected?The Journal of the American Association of Gynecologic Laparoscopists, 1999
- Uterine Side Effects of Tamoxifen: A Need for Systematic Pretreatment ScreeningObstetrics & Gynecology, 1998
- Uncommon Forms of Genital TuberculosisObstetrics & Gynecology, 1962