Alkaloids from the Roots of Zanthoxylum nitidum and Their Antiviral and Antifungal Effects
- 24 September 2008
- journal article
- research article
- Published by Wiley in Chemistry & Biodiversity
- Vol. 5 (9), 1718-1722
- https://doi.org/10.1002/cbdv.200890160
Abstract
Five alkaloids, 5,6-dihydro-6-methoxynitidine (1), dictamnine (2), γ-fagarine (3), skimmianine (4), and 5-methoxydictamnine (5), were isolated from the roots of Zanthoxylum nitidum. Their structures and configurations were elucidated by spectroscopic methods and X-ray analysis. Compounds 1, 4, and 5 showed in vitro antiviral effect against hepatitis B virus, and compounds 2, 3, and 5 demonstrated marked antimitotic and antifungal activity.Keywords
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